INT232980

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Context Info
Confidence 0.29
First Reported 2008
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.43
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (KRT3) cytoskeleton organization (KRT3)
KRT3 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 2 32.00 Quite Low
Inflammation 9 5.00 Very Low Very Low Very Low
medulla 7 5.00 Very Low Very Low Very Low
Pain 5 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
peripheral neuropathy 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 19 92.04 High High
Alzheimer's Dementia 7 61.00 Quite High
Disease 38 57.76 Quite High
Ichthyosis 3 55.64 Quite High
Injury 13 51.36 Quite High
Cancer 87 46.40 Quite Low
Blister 4 36.24 Quite Low
Amyloid Plaque 5 33.48 Quite Low
Fibrosis 3 32.00 Quite Low
Keloid Scars 2 31.04 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Antibodies against these corneal keratins described include MAb AE5 (PROGEN, Heidelberg, Germany) which reacts with K3 and additionally with the related K76 (formerly K2p; see below; Collin et al. 1992b) and MAb AK12 which recognizes K12 (Chaloin-Dufau et al. 1993).


K3 Binding (reacts) of
1) Confidence 0.29 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2386534 Disease Relevance 0.20 Pain Relevance 0
As expected because of the mode of inheritance it is not linked to the KRT3 and KRT12 genes.
KRT3 Binding (linked) of
2) Confidence 0.21 Published 2009 Journal Orphanet J Rare Dis Section Body Doc Link PMC2695576 Disease Relevance 0.23 Pain Relevance 0

General Comments

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