INT232995

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Context Info
Confidence 0.32
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.37
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
keratinocytes 2
KRT15 (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 1 5.68 Low Low
medulla 7 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
Chronic pancreatitis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 19 86.00 High High
Cancer 85 79.36 Quite High
Basal Cell Carcinoma 3 67.44 Quite High
Adenocarcinoma 46 25.88 Quite Low
Breast Cancer 11 20.32 Low Low
Skin Cancer 29 5.00 Very Low Very Low Very Low
Carcinoma 22 5.00 Very Low Very Low Very Low
Metastasis 16 5.00 Very Low Very Low Very Low
Disease 13 5.00 Very Low Very Low Very Low
Injury 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
K15 expression in basal cells is downregulated in activated epidermal keratinocytes such as in organotypic cultures and in hyperproliferation (Waseem et al. 1999) or upon wounding (Porter et al. 2000).
Negative_regulation (downregulated) of Gene_expression (expression) of K15 in keratinocytes
1) Confidence 0.32 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2386534 Disease Relevance 0.37 Pain Relevance 0

General Comments

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