INT233127

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Context Info
Confidence 0.11
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.91
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mRNA processing (AICDA) cytoplasm (AICDA)
Anatomy Link Frequency
grid 2
T cells 2
AICDA (Homo sapiens)
Pain Link Frequency Relevance Heat
Multiple sclerosis 12 88.88 High High
chemokine 1 87.72 High High
cytokine 1 87.12 High High
Inflammation 1 85.84 High High
Central nervous system 1 85.04 High High
cerebral cortex 3 68.00 Quite High
spinal inflammation 8 5.00 Very Low Very Low Very Low
rheumatoid arthritis 7 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Autoimmune Disease 45 100.00 Very High Very High Very High
Systemic Lupus Erythematosus 6 98.48 Very High Very High Very High
Demyelinating Disease 12 88.88 High High
INFLAMMATION 1 85.84 High High
Diabetes Mellitus 17 70.96 Quite High
Disease 23 56.16 Quite High
Disease Susceptibility 4 37.96 Quite Low
Unconsciousness 3 25.92 Quite Low
Epilepsy 3 23.96 Low Low
Coma 6 22.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Further models suggested a key role for CD8+ T cells in AID progression, rather than in initiation [63, 64].
Positive_regulation (role) of Gene_expression (progression) of AID in T cells associated with autoimmune disease
1) Confidence 0.11 Published 2007 Journal Current Genomics Section Body Doc Link PMC2647156 Disease Relevance 0.91 Pain Relevance 0.25
The inefficiency increases with the size of the grid; for example an XOR-grid of a million elements is needed to generate 1000 bits of integrated information. ?
Positive_regulation (generate) of Gene_expression (generate) of integrated in grid
2) Confidence 0.03 Published 2008 Journal PLoS Computational Biology Section Body Doc Link PMC2386970 Disease Relevance 0 Pain Relevance 0
requires functionally integrated and functionally specialized networks
Positive_regulation (requires) of Gene_expression (networks) of integrated
3) Confidence 0.03 Published 2008 Journal PLoS Computational Biology Section Body Doc Link PMC2386970 Disease Relevance 0 Pain Relevance 0
is a causal measure: integrated information is generated only to the extent that the system transitions into a given state due to causal interactions among its elements.
Positive_regulation (generated) of Gene_expression (generated) of integrated
4) Confidence 0.03 Published 2008 Journal PLoS Computational Biology Section Body Doc Link PMC2386970 Disease Relevance 0 Pain Relevance 0.03

General Comments

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