INT233218

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Context Info
Confidence 0.31
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.09
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Hoxa10) DNA binding (Hoxa10)
Anatomy Link Frequency
uterine 2
embryo 1
adult uterus 1
Hoxa10 (Mus musculus)
Pain Link Frequency Relevance Heat
endometriosis 3 38.16 Quite Low
anesthesia 3 5.00 Very Low Very Low Very Low
cva 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Reprotox - General 3 3 92.36 High High
Endometriosis (extended) 3 38.16 Quite Low
Ovarian Cancer 3 36.96 Quite Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 3 26.96 Quite Low
Leukemia 15 5.00 Very Low Very Low Very Low
Acute Myeloid Leukemia 12 5.00 Very Low Very Low Very Low
Cancer 9 5.00 Very Low Very Low Very Low
Hypersensitivity 9 5.00 Very Low Very Low Very Low
Neuroblastoma 6 5.00 Very Low Very Low Very Low
Anaemia 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hoxa10 expression persists in the adult uterus and is important for implantation of the embryo.
Regulation (important) of in embryo Gene_expression (expression) of Hoxa10 in adult uterus
1) Confidence 0.31 Published 2008 Journal Human Reproduction (Oxford, England) Section Body Doc Link PMC2387222 Disease Relevance 0 Pain Relevance 0
In the developing mouse embryo, altered Hoxa10 expression as a result of targeted mutation (Satokata et al., 1995) or exposure to diethylstilbestrol leads to abnormal uterine development (Block et al., 2000).
Regulation (altered) of Gene_expression (expression) of Hoxa10 in uterine
2) Confidence 0.19 Published 2008 Journal Human Reproduction (Oxford, England) Section Body Doc Link PMC2387222 Disease Relevance 0 Pain Relevance 0
In humans, HOXA10 expression is up-regulated in the mid-luteal phase at the time of implantation, and its expression is driven by estrogen and progesterone (Taylor et al., 1998).
Regulation (regulated) of Gene_expression (expression) of HOXA10
3) Confidence 0.19 Published 2008 Journal Human Reproduction (Oxford, England) Section Body Doc Link PMC2387222 Disease Relevance 0.09 Pain Relevance 0

General Comments

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