INT233460

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Context Info
Confidence 0.34
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.30
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (P2ry14) plasma membrane (P2ry14) signal transducer activity (P2ry14)
Anatomy Link Frequency
hematopoietic stem cells 2
P2ry14 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 14 99.60 Very High Very High Very High
Inflammatory response 12 83.84 Quite High
Glutamate 20 74.72 Quite High
Central nervous system 7 72.96 Quite High
Neurotransmitter 3 69.92 Quite High
adenocard 28 50.76 Quite High
antagonist 4 31.72 Quite Low
medulla 1 23.84 Low Low
cerebral cortex 1 22.92 Low Low
Glutamate receptor 4 22.48 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 43 83.84 Quite High
Neurodegenerative Disease 1 16.16 Low Low
Pain 2 14.96 Low Low
Injury 5 14.04 Low Low
Epilepsy 29 6.00 Low Low
Convulsion 11 5.00 Very Low Very Low Very Low
Depression 7 5.00 Very Low Very Low Very Low
Mycobacterial Infection 6 5.00 Very Low Very Low Very Low
Disease 6 5.00 Very Low Very Low Very Low
Necrosis 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Finally, the P2Y-like receptor, P2ry14 (Gpr105), which is a receptor for UDP-conjugated sugars, mediated chemotaxis of bone marrow hematopoietic stem cells [33].
Gpr105 Binding (receptor) of in hematopoietic stem cells
1) Confidence 0.34 Published 2008 Journal Immunome Res Section Body Doc Link PMC2394514 Disease Relevance 0.15 Pain Relevance 0.19
Finally, the P2Y-like receptor, P2ry14 (Gpr105), which is a receptor for UDP-conjugated sugars, mediated chemotaxis of bone marrow hematopoietic stem cells [33].
P2ry14 Binding (receptor) of in hematopoietic stem cells
2) Confidence 0.34 Published 2008 Journal Immunome Res Section Body Doc Link PMC2394514 Disease Relevance 0.15 Pain Relevance 0.19
In addition, a key role for P2X7 receptors is established as well as possibly contributory roles for P2X2, P2X4, P2X5, P2Y2, P2Y4 and P2Y14 based on agonist preferences [40].
P2Y14 Binding (roles) of associated with agonist
3) Confidence 0.13 Published 2008 Journal Purinergic Signal Section Body Doc Link PMC2583203 Disease Relevance 0 Pain Relevance 0.18

General Comments

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