INT233462

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Context Info
Confidence 0.45
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Fzd1) plasma membrane (Fzd1) cell-cell signaling (Fzd1)
cytoplasm (Fzd1) signal transducer activity (Fzd1)
Anatomy Link Frequency
macrophage 1
Fzd1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 6 95.40 Very High Very High Very High
Inflammation 11 59.08 Quite High
chemokine 2 45.24 Quite Low
agonist 6 5.00 Very Low Very Low Very Low
Inflammatory stimuli 4 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 21 95.40 Very High Very High Very High
Mycobacterial Infection 3 94.28 High High
Adhesions 1 80.56 Quite High
Cancer 2 44.72 Quite Low
Necrosis 2 44.24 Quite Low
Demyelinating Disease 1 5.00 Very Low Very Low Very Low
Hypoxia 1 5.00 Very Low Very Low Very Low
Repression 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The striking up-regulation of Fzd1 in BMM (17-fold at 6 h LPS) implies that this FZD family member shares similar functions in regulating macrophage inflammatory responses.
Regulation (regulation) of Fzd1 in macrophage associated with inflammatory response
1) Confidence 0.45 Published 2008 Journal Immunome Res Section Body Doc Link PMC2394514 Disease Relevance 0.33 Pain Relevance 0.08

General Comments

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