INT233475
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
The co-regulated expression of receptors such as Gpr85 in neural tissues and leukocyte populations may provide a mechanism for the neuro-immune cross-talk that has been observed in several studies [41,42]. | |||||||||||||||
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Whilst the expression of Gpr85 in the central nervous system was previously reported [38-40], a function has yet to be identified. | |||||||||||||||
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For example, Gpr85 was highly expressed in several macrophage populations and was further up-regulated by LPS, but was also expressed in several regions of the brain (Figure 1a). | |||||||||||||||
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Expression of the SREB (super conserved receptor expressed in brain) family member Gpr85 (Sreb2) was restricted to macrophages and neuronal tissues (Figure 1a). | |||||||||||||||
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For example, Gpr85 was highly expressed in several macrophage populations and was further up-regulated by LPS, but was also expressed in several regions of the brain (Figure 1a). | |||||||||||||||
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Expression of the SREB (super conserved receptor expressed in brain) family member Gpr85 (Sreb2) was restricted to macrophages and neuronal tissues (Figure 1a). | |||||||||||||||
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Other GPCRs that had a relatively restricted expression pattern and were strongly expressed by macrophages include Edg5, Gpr85 and Gpr84 (Table 2, Figure 1a and 1c, Additional file 2b). | |||||||||||||||
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Expression of the SREB (super conserved receptor expressed in brain) family member Gpr85 (Sreb2) was restricted to macrophages and neuronal tissues (Figure 1a). | |||||||||||||||
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Expression of the SREB (super conserved receptor expressed in brain) family member Gpr85 (Sreb2) was restricted to macrophages and neuronal tissues (Figure 1a). | |||||||||||||||
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