INT233486

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Context Info
Confidence 0.29
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.07
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Lpar6) plasma membrane (Lpar6) molecular_function (Lpar6)
biological_process (Lpar6) signal transducer activity (Lpar6)
Anatomy Link Frequency
macrophages 1
Lpar6 (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 2 96.12 Very High Very High Very High
Inflammatory response 6 74.60 Quite High
agonist 6 45.00 Quite Low
Inflammatory stimuli 4 8.76 Low Low
Inflammation 11 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 21 74.20 Quite High
Hypoxia 1 10.88 Low Low
Injury 1 7.88 Low Low
Stress 1 7.20 Low Low
Mycobacterial Infection 3 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Cancer 2 5.00 Very Low Very Low Very Low
Demyelinating Disease 1 5.00 Very Low Very Low Very Low
Repression 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Down-regulation of P2RY5 in response to a macrophage activating stimulus such as LPS might remove this inhibitory effect, thus allowing activated macrophages to respond to nucleotides.
Negative_regulation (regulation) of P2RY5 in macrophages
1) Confidence 0.29 Published 2008 Journal Immunome Res Section Body Doc Link PMC2394514 Disease Relevance 0.07 Pain Relevance 0.11

General Comments

This test has worked.

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