INT233489

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Context Info
Confidence 0.38
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 0.74
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Ccrl2) plasma membrane (Ccrl2) signal transducer activity (Ccrl2)
Anatomy Link Frequency
spleen 4
Ccrl2 (Mus musculus)
Pain Link Frequency Relevance Heat
chemokine 149 100.00 Very High Very High Very High
ischemia 9 91.72 High High
Inflammation 44 56.08 Quite High
Inflammatory response 17 28.40 Quite Low
cytokine 15 5.00 Very Low Very Low Very Low
agonist 8 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
Inflammatory stimuli 4 5.00 Very Low Very Low Very Low
Potency 4 5.00 Very Low Very Low Very Low
anesthesia 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 67 99.44 Very High Very High Very High
Cv Unclassified Under Development 9 91.72 High High
Repression 1 84.32 Quite High
Disease 7 56.88 Quite High
INFLAMMATION 65 56.08 Quite High
Reperfusion Injury 1 50.00 Quite Low
Wound Healing 3 36.96 Quite Low
Increased Venous Pressure Under Development 2 7.64 Low Low
Anaphylaxis 58 5.00 Very Low Very Low Very Low
Edema 38 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Gpr109b/PUMA-G, Fpr1, Ccrl2 and Ednrb) ([12-16], Sweet et al, unpublished data), regulated expression of others has not been widely studied.
Regulation (regulated) of Gene_expression (expression) of Ccrl2
1) Confidence 0.38 Published 2008 Journal Immunome Res Section Body Doc Link PMC2394514 Disease Relevance 0.08 Pain Relevance 0
CCRL2 gene expression was normalized to cyclophilin A (cycA) levels in each tissue and displayed relative to CCRL2 expression levels detected in the spleen using the 2???
Regulation (normalized) of Gene_expression (expression) of CCRL2 in spleen
2) Confidence 0.33 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2556791 Disease Relevance 0.06 Pain Relevance 0
CCRL2 gene expression was normalized to cyclophilin A (cycA) levels in each tissue and displayed relative to CCRL2 expression levels detected in the spleen using the 2???
Regulation (displayed) of Gene_expression (expression) of CCRL2 in spleen
3) Confidence 0.33 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2556791 Disease Relevance 0.06 Pain Relevance 0
In the present study, we identified chemokine, chemokine receptor and chemokine-related genes whose expression is affected in renal I/R injury.
Regulation (affected) of Gene_expression (expression) of chemokine-related associated with chemokine and injury
4) Confidence 0.01 Published 2010 Journal International Immunology Section Body Doc Link PMC2877810 Disease Relevance 0.54 Pain Relevance 0.49

General Comments

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