INT233496

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Context Info
Confidence 0.21
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 1.34
Pain Relevance 0.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Gpbar1) plasma membrane (Gpbar1) signal transducer activity (Gpbar1)
Anatomy Link Frequency
macrophages 10
Gpbar1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 66 98.88 Very High Very High Very High
Inflammatory stimuli 24 94.56 High High
Inflammatory response 36 5.00 Very Low Very Low Very Low
agonist 36 5.00 Very Low Very Low Very Low
adenocard 18 5.00 Very Low Very Low Very Low
chemokine 12 5.00 Very Low Very Low Very Low
antagonist 12 5.00 Very Low Very Low Very Low
cytokine 6 5.00 Very Low Very Low Very Low
Central nervous system 6 5.00 Very Low Very Low Very Low
Analgesic 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 6 99.20 Very High Very High Very High
INFLAMMATION 126 98.88 Very High Very High Very High
Repression 6 96.36 Very High Very High Very High
Mycobacterial Infection 18 5.00 Very Low Very Low Very Low
Necrosis 12 5.00 Very Low Very Low Very Low
Cancer 12 5.00 Very Low Very Low Very Low
Demyelinating Disease 6 5.00 Very Low Very Low Very Low
Hypoxia 6 5.00 Very Low Very Low Very Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Adhesions 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
LPS-regulated GPCR expression in mouse macrophages
Regulation (regulated) of Gene_expression (expression) of GPCR in macrophages
1) Confidence 0.21 Published 2008 Journal Immunome Res Section Body Doc Link PMC2394514 Disease Relevance 0.05 Pain Relevance 0
Figure 3 highlights two examples of regulated GPCR expression: mRNA expression of Gpr84 was induced 10-fold by LPS (6 h) in BMM and 48-fold by LPS (7 h) in TEPM (Figure 3a), whilst P2ry1 was repressed 7-fold by LPS (6 h) in BMM and 18-fold by LPS (7 h) in TEPM (Figure 3b).
Regulation (regulated) of Gene_expression (expression) of GPCR
2) Confidence 0.21 Published 2008 Journal Immunome Res Section Body Doc Link PMC2394514 Disease Relevance 0.10 Pain Relevance 0
Differential GPCR expression in distinct macrophage populations
Regulation (Differential) of Gene_expression (expression) of GPCR in macrophage
3) Confidence 0.16 Published 2008 Journal Immunome Res Section Body Doc Link PMC2394514 Disease Relevance 0.18 Pain Relevance 0.09
Differential GPCR expression in distinct macrophage populations
Regulation (populations) of Gene_expression (expression) of GPCR in macrophage
4) Confidence 0.16 Published 2008 Journal Immunome Res Section Body Doc Link PMC2394514 Disease Relevance 0.19 Pain Relevance 0.09
Constitutive GPCR expression in mouse macrophages
Regulation (macrophages) of Gene_expression (expression) of GPCR in macrophages
5) Confidence 0.14 Published 2008 Journal Immunome Res Section Body Doc Link PMC2394514 Disease Relevance 0.41 Pain Relevance 0.16
Constitutive GPCR expression in mouse macrophages
Regulation (Constitutive) of Gene_expression (expression) of GPCR in macrophages
6) Confidence 0.14 Published 2008 Journal Immunome Res Section Body Doc Link PMC2394514 Disease Relevance 0.41 Pain Relevance 0.16

General Comments

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