INT233510

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Wnt5a, Il12a) extracellular region (Wnt5a, Il12a) cytoplasm (Wnt5a, Il12a)
cell differentiation (Wnt5a) signal transduction (Wnt5a) proteinaceous extracellular matrix (Wnt5a)
Anatomy Link Frequency
mononuclear cells 2
Wnt5a (Mus musculus)
Il12a (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammatory response 6 84.32 Quite High
Inflammation 11 63.88 Quite High
chemokine 2 50.04 Quite High
Multiple sclerosis 1 7.88 Low Low
agonist 6 5.00 Very Low Very Low Very Low
Inflammatory stimuli 4 5.00 Very Low Very Low Very Low
adenocard 3 5.00 Very Low Very Low Very Low
antagonist 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mycobacterial Infection 3 99.54 Very High Very High Very High
Adhesions 1 85.36 High High
INFLAMMATION 21 84.32 Quite High
Cancer 2 38.24 Quite Low
Necrosis 2 37.76 Quite Low
Demyelinating Disease 1 7.88 Low Low
Multiple Sclerosis 1 6.76 Low Low
Hypoxia 1 5.00 Very Low Very Low Very Low
Repression 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In human macrophages, WNT5A expression was up-regulated by TLR ligands, as well as challenge with M. tuberculosis and M. avium, and the WNT5A/Frizzled-5 (FZD5) pathway promoted IL-12 production from peripheral blood mononuclear cells [52].
WNT5A Positive_regulation (promoted) of Gene_expression (production) of IL-12 in mononuclear cells associated with mycobacterial infection
1) Confidence 0.03 Published 2008 Journal Immunome Res Section Body Doc Link PMC2394514 Disease Relevance 0.33 Pain Relevance 0.10

General Comments

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