INT233562

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Context Info
Confidence 0.23
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.81
Pain Relevance 0.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (Fabp5) transport (Fabp5) lipid metabolic process (Fabp5)
cytoplasm (Fabp5)
Fabp5 (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 9 73.48 Quite High
Hippocampus 1 62.72 Quite High
chemokine 1 50.08 Quite High
alcohol 3 43.32 Quite Low
Paracetamol 4 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
halothane 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shock 1 99.32 Very High Very High Very High
Cancer 140 97.64 Very High Very High Very High
Sprains And Strains 125 97.36 Very High Very High Very High
Metastasis 6 95.68 Very High Very High Very High
Malignant Neoplastic Disease 14 83.00 Quite High
Papillomavirus Infection 19 76.40 Quite High
Nicotine Addiction 1 73.20 Quite High
Pharynx Cancer 3 52.00 Quite High
Skin Cancer 10 50.00 Quite Low
Targeted Disruption 9 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several genes exhibiting strain-dependent differences in prostate expression have been studied in the context of prostate development (for example, Sbp), androgen regulation (Fabp5, Odc), tumorigenesis (for example, Psca, Azgp1, Apod, Mmp7, Egf, Mgst1, Clusterin), and the progression of metastatic cancer (Cxcl12, B2m, H2 family members) [8].
Regulation (regulation) of Fabp5 associated with sprains and strains and metastasis
1) Confidence 0.23 Published 2007 Journal Genome Biol Section Body Doc Link PMC2394769 Disease Relevance 0.99 Pain Relevance 0.03
It is possible that up regulation of FABP5 occurred at the expense of MUP6 synthesis, which then showed a marked fall in expression; further work is required to understand the interaction between these proteins and the precise role of Nrf2.
Spec (possible) Regulation (regulation) of FABP5
2) Confidence 0.21 Published 2010 Journal Journal of Proteomics Section Body Doc Link PMC2891861 Disease Relevance 0 Pain Relevance 0
In addition, specific up-regulated genes including CD24, E-cadherin, FABP5, keratins, heat shock protein (27 kDa), and others identified by microarray analysis were also identified by flow cytometry and immunostaining.
Regulation (regulated) of FABP5 associated with shock
3) Confidence 0.12 Published 2010 Journal Head Neck Oncol Section Body Doc Link PMC2841166 Disease Relevance 0.83 Pain Relevance 0.09

General Comments

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