INT233570

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Context Info
Confidence 0.66
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.40
Pain Relevance 0.17

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Rbp4) extracellular space (Rbp4) extracellular region (Rbp4)
embryo development (Rbp4) transmembrane transport (Rbp4)
Anatomy Link Frequency
blood 1
Clara cell 1
Rbp4 (Mus musculus)
Pain Link Frequency Relevance Heat
abdominal pain 1 89.16 High High
Pain 1 85.44 High High
Inflammatory response 18 50.00 Quite Low
Inflammation 21 5.00 Very Low Very Low Very Low
tolerance 18 5.00 Very Low Very Low Very Low
agonist 11 5.00 Very Low Very Low Very Low
anesthesia 5 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
isoflurane 4 5.00 Very Low Very Low Very Low
alcohol 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 72 99.22 Very High Very High Very High
Prostate Cancer 27 96.60 Very High Very High Very High
Proteinuria 16 96.48 Very High Very High Very High
Abdominal Pain 1 89.16 High High
Rickets 10 87.08 High High
Pain 1 85.44 High High
Night Blindness 2 85.20 High High
Aging 1 84.12 Quite High
Disease 56 82.52 Quite High
Kidney Stones 41 82.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, transcript levels of four C57-Low genes (for example, Esr1) in benign prostate tissues were significantly associated with low-grade cancers and five C57-High genes (for example, Rbp4) were expressed at greater levels in benign tissue associated with high-grade relative to low-grade prostate cancers (Figure 5b).
Gene_expression (expressed) of Rbp4 associated with cancer and prostate cancer
1) Confidence 0.66 Published 2007 Journal Genome Biol Section Body Doc Link PMC2394769 Disease Relevance 1.42 Pain Relevance 0
Key mediators of insulin and glucose metabolism such as the retinol-binding protein 4 (RBP4) were also regulated in ?
Gene_expression (Key) of RBP4
2) Confidence 0.54 Published 2008 Journal PLoS Genetics Section Body Doc Link PMC2432036 Disease Relevance 0 Pain Relevance 0
2 microglobulins, retinol-binding protein (RBP), Clara cell protein, and vitamin D binding protein, is found in approximately 99% of affected males.
Gene_expression (retinol-binding protein) of RBP in Clara cell
3) Confidence 0.27 Published 2010 Journal Orphanet J Rare Dis Section Body Doc Link PMC2964617 Disease Relevance 1.98 Pain Relevance 0.17
However, stimulated by retinoic acid 6 (Stra6), which is identified as a receptor for the blood retinol carrier; retinol-binding protein (Rbp) [46], was not significantly differentially expressed on the microarrays between the BC-supplemented and control diet-fed mice.
Neg (not) Gene_expression (expressed) of Rbp in blood
4) Confidence 0.27 Published 2010 Journal Cell Mol Life Sci Section Body Doc Link PMC2877315 Disease Relevance 0 Pain Relevance 0

General Comments

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