INT233638

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Context Info
Confidence 0.56
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.01
Pain Relevance 1.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nfkbia) plasma membrane (Nfkbia) nucleus (Nfkbia)
enzyme binding (Nfkbia) protein complex (Nfkbia) cytoplasm (Nfkbia)
Nfkbia (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 344 99.98 Very High Very High Very High
antagonist 12 69.52 Quite High
Glutamate receptor 2 67.52 Quite High
Neuropeptide 2 65.84 Quite High
Opioid 56 5.00 Very Low Very Low Very Low
Physical dependence 20 5.00 Very Low Very Low Very Low
withdrawal 18 5.00 Very Low Very Low Very Low
addiction 16 5.00 Very Low Very Low Very Low
tolerance 16 5.00 Very Low Very Low Very Low
Eae 14 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sprains And Strains 164 99.96 Very High Very High Very High
Adhesions 2 81.80 Quite High
Skin Cancer 2 81.24 Quite High
Shock 16 79.36 Quite High
Nervous System Malformation 8 72.28 Quite High
Apoptosis 16 34.84 Quite Low
Drug Dependence 24 5.00 Very Low Very Low Very Low
Opiate Addiction 16 5.00 Very Low Very Low Very Low
Stress 6 5.00 Very Low Very Low Very Low
Decapitation 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Uniquely in the C57BL/6J strain, abundance of Nfkbia mRNA was increased almost twofold after acute morphine compared with control.
Positive_regulation (increased) of Transcription (abundance) of Nfkbia associated with sprains and strains and morphine
1) Confidence 0.56 Published 2007 Journal Genome Biol Section Body Doc Link PMC2394777 Disease Relevance 0.71 Pain Relevance 0.42
The qPCR method was used to evaluate the influence of GR blockade on acute morphine-induced gene transcription of selected genes (Tsc22d3, Nfkbia, Zbtb16, Sgk, and Fzd2).
Positive_regulation (induced) of Transcription (transcription) of Nfkbia associated with morphine
2) Confidence 0.46 Published 2007 Journal Genome Biol Section Body Doc Link PMC2394777 Disease Relevance 0.30 Pain Relevance 0.91

General Comments

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