INT233665

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Context Info
Confidence 0.49
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.30
Pain Relevance 1.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Sgk1) endoplasmic reticulum (Sgk1) plasma membrane (Sgk1)
nucleus (Sgk1) kinase activity (Sgk1) response to stress (Sgk1)
Sgk1 (Mus musculus)
Pain Link Frequency Relevance Heat
Morphine 190 99.98 Very High Very High Very High
antagonist 14 70.56 Quite High
Nucleus accumbens 6 55.52 Quite High
Opioid 35 5.00 Very Low Very Low Very Low
addiction 22 5.00 Very Low Very Low Very Low
cocaine 20 5.00 Very Low Very Low Very Low
Physical dependence 10 5.00 Very Low Very Low Very Low
withdrawal 9 5.00 Very Low Very Low Very Low
Nicotine 9 5.00 Very Low Very Low Very Low
Eae 9 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 1 81.80 Quite High
Skin Cancer 1 81.24 Quite High
Nervous System Malformation 4 72.28 Quite High
Sprains And Strains 82 66.68 Quite High
Apoptosis 9 34.84 Quite Low
Shock 10 17.12 Low Low
Drug Dependence 15 5.00 Very Low Very Low Very Low
Stress 11 5.00 Very Low Very Low Very Low
Opiate Addiction 8 5.00 Very Low Very Low Very Low
Decapitation 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, transcription of Sgk1 and Tsc22d3 was not activated during the behavioral expression of morphine-induced CPP (Figure 3b).
Neg (not) Positive_regulation (activated) of Transcription (transcription) of Sgk1 associated with morphine
1) Confidence 0.49 Published 2010 Journal Genome Biol Section Body Doc Link PMC2898085 Disease Relevance 0 Pain Relevance 0.38
The qPCR method was used to evaluate the influence of GR blockade on acute morphine-induced gene transcription of selected genes (Tsc22d3, Nfkbia, Zbtb16, Sgk, and Fzd2).
Positive_regulation (induced) of Transcription (transcription) of Sgk associated with morphine
2) Confidence 0.44 Published 2007 Journal Genome Biol Section Body Doc Link PMC2394777 Disease Relevance 0.30 Pain Relevance 0.91

General Comments

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