INT233808

Context Info Confidence 0.49 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

transport (Slc52a2) plasma membrane (Slc52a2)

Slc52a2 (Mus musculus)

Pain Link Frequency Relevance Heat Glutamate 11 5.00 chemokine 7 5.00 Cannabinoid receptor 2 5.00 Glutamate receptor 2 5.00 Somatostatin 2 5.00 Cannabinoid 2 5.00 Peripheral nervous system 1 5.00 GABA receptor 1 5.00 adenocard 1 5.00 Pain 1 5.00

Disease Link Frequency Relevance Heat Adhesions 35 5.00 Disease 4 5.00 Multiple System Atrophy 4 5.00 Hypercalcemia 2 5.00 Pain 1 5.00 Syndrome 1 5.00 Targeted Disruption 1 5.00 Diabetes Insipidus 1 5.00 Chondrodysplasia 1 5.00 Aging 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In vertebrate INSL3/relaxin binding GPCRs, a combination of a single cysteine-rich LDL-A domain and multiple LRRs at the ectodomain site is necessary for ligand binding, receptor activation and further downstream signalling from these receptors [45].

Positive_regulation (necessary) of GPCR Binding (binding) of

1) Confidence 0.49 Published 2008 Journal BMC Evol Biol Section Body Doc Link PMC2396169 Disease Relevance 0 Pain Relevance 0

General Comments

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