INT233836

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Context Info
Confidence 0.17
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.90
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Mapk7) cytosol (Mapk7) nucleus (Mapk7)
cell cycle (Mapk7) kinase activity (Mapk7) cytoplasm (Mapk7)
Anatomy Link Frequency
hinge 1
neurons 1
Mapk7 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 2 96.12 Very High Very High Very High
cytokine 4 35.88 Quite Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Cholecystokinin 1 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
GABAergic 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Lung Cancer 39 97.28 Very High Very High Very High
INFLAMMATION 2 96.12 Very High Very High Very High
Non-small-cell Lung Cancer 24 81.60 Quite High
Cancer 25 70.04 Quite High
Metastasis 8 66.64 Quite High
Targeted Disruption 3 22.72 Low Low
Nicotine Addiction 2 6.32 Low Low
Myopia 13 5.00 Very Low Very Low Very Low
Small Cell Lung Cancer 8 5.00 Very Low Very Low Very Low
Adenocarcinoma 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
involves direct binding of ERK5 to the hinge region of PPAR?.
ERK5 Binding (binding) of in hinge
1) Confidence 0.17 Published 2008 Journal PPAR Research Section Body Doc Link PMC2396386 Disease Relevance 0.90 Pain Relevance 0.05
It is expressed exclusively in neurons and binds preferentially to JNK3 and also to the MAPK kinase 7 [73].


MAPK kinase 7 Binding (binds) of in neurons
2) Confidence 0.06 Published 2007 Journal Molecular Vision Section Body Doc Link PMC2774458 Disease Relevance 0 Pain Relevance 0

General Comments

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