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Context Info
Confidence 0.60
First Reported 2008
Last Reported 2011
Negated 1
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.25
Pain Relevance 0.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SFTPC) extracellular region (SFTPC) cytoplasm (SFTPC)
Anatomy Link Frequency
lungs 1
respiratory 1
SFTPC (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 101 92.96 High High
cytokine 22 64.56 Quite High
Inflammation 36 37.96 Quite Low
chemokine 7 26.00 Quite Low
Inflammatory response 5 5.00 Very Low Very Low Very Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Spinal cord 2 5.00 Very Low Very Low Very Low
ketamine 2 5.00 Very Low Very Low Very Low
Versed 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 20 99.36 Very High Very High Very High
Lung Cancer 39 97.32 Very High Very High Very High
Pulmonary Fibrosis 68 92.96 High High
Heterotopic Ossification 87 92.28 High High
Hyperoxia 1 88.72 High High
Respiratory Failure 5 85.28 High High
Lung Injury 24 85.20 High High
Respiratory Distress 1 80.24 Quite High
Congenital Anomalies 5 74.88 Quite High
Injury 33 69.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
under the control of the surfactant protein C promoter, which
Regulation (control) of surfactant protein C
1) Confidence 0.60 Published 2008 Journal PPAR Research Section Body Doc Link PMC2396386 Disease Relevance 0.57 Pain Relevance 0
Both, total SP-B and SP-C concentrations were not statistically different between the experimental groups.
Neg (not) Regulation (different) of SP-C
2) Confidence 0.44 Published 2008 Journal BMC Pulm Med Section Body Doc Link PMC2483254 Disease Relevance 0 Pain Relevance 0
While STAT-3 deletion in mice is lethal, the selective deletion of STAT-3 gene in respiratory epithelial cells by conditional expression of Cre-recombinase under control of the surfactant protein C gene promoter did not alter prenatal lung morphogenesis or postnatal lung function [104].
Regulation (control) of surfactant protein C in respiratory
3) Confidence 0.44 Published 2010 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2940818 Disease Relevance 0.69 Pain Relevance 0.19
Transgenic mice overexpressing BMP4 under control of surfactant protein-C gene promoter die from abnormally formed lungs [57].
Regulation (control) of surfactant protein-C in lungs associated with targeted disruption
4) Confidence 0.44 Published 2011 Journal Journal of Biomedicine and Biotechnology Section Body Doc Link PMC2963134 Disease Relevance 0.98 Pain Relevance 0

General Comments

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