INT233858

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Context Info
Confidence 0.10
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (CHKA, CDKN1B) endosome (CDKN1B) nucleoplasm (CDKN1B)
lipid metabolic process (CHKA) signal transducer activity (CHKA) cytosol (CDKN1B)
CHKA (Homo sapiens)
CDKN1B (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 12 62.80 Quite High
fibrosis 7 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
Bile 1 5.00 Very Low Very Low Very Low
palliative 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hepatocellular Cancer 26 64.92 Quite High
Cirrhosis 16 54.28 Quite High
Nash(non-alcoholic Steatohepatitis) 3 39.04 Quite Low
Chronic Hepatitis 1 35.64 Quite Low
Malignant Neoplastic Disease 1 19.68 Low Low
Cancer 14 5.00 Very Low Very Low Very Low
Apoptosis 7 5.00 Very Low Very Low Very Low
Fibrosis 5 5.00 Very Low Very Low Very Low
Death 5 5.00 Very Low Very Low Very Low
Hepatitis C Virus Infection 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
increase in the mRNA and protein expression of the Cyclin-dependent kinase inhibitor (Cki) p21waf1/cip1 and also an increase in protein expression only of p27kip1, another CKi.
Cki Positive_regulation (increase) of Gene_expression (expression) of p27kip1
1) Confidence 0.10 Published 2008 Journal PPAR Research Section Body Doc Link PMC2396389 Disease Relevance 0.17 Pain Relevance 0.09

General Comments

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