INT2339

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.29
First Reported 1977
Last Reported 2010
Negated 3
Speculated 3
Reported most in Abstract
Documents 30
Total Number 33
Disease Relevance 10.68
Pain Relevance 9.12

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
blood 23
neuronal 1
fastigial nucleus 1
grey matter 1
brain 1
CB (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 58 100.00 Very High Very High Very High
ischemia 20 100.00 Very High Very High Very High
isoflurane 26 99.84 Very High Very High Very High
ketamine 6 99.80 Very High Very High Very High
halothane 26 99.68 Very High Very High Very High
cva 19 99.68 Very High Very High Very High
adenocard 10 99.36 Very High Very High Very High
Pain 8 99.12 Very High Very High Very High
antagonist 10 98.48 Very High Very High Very High
headache 8 98.40 Very High Very High Very High
Disease Link Frequency Relevance Heat
Cv Unclassified Under Development 10 100.00 Very High Very High Very High
Sleep Disorders 9 99.98 Very High Very High Very High
Cv General 3 Under Development 14 99.68 Very High Very High Very High
Diabetes Mellitus 4 99.56 Very High Very High Very High
Brain Hemorrhage 13 99.48 Very High Very High Very High
Atherosclerosis 1 99.34 Very High Very High Very High
Pain 7 99.12 Very High Very High Very High
Convulsion 4 98.92 Very High Very High Very High
Increased Venous Pressure Under Development 7 98.84 Very High Very High Very High
Tauopathy 40 98.80 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Practitioners wield several tools that upregulate eCB activity, including myofascial manipulation, diet and lifestyle modifications, and pharmaceutical approaches.
Positive_regulation (upregulate) of eCB
1) Confidence 0.29 Published 2008 Journal J Bodyw Mov Ther Section Abstract Doc Link 19083670 Disease Relevance 0.75 Pain Relevance 0.47
Patients with SCD in vaso-occlusive crisis had PMN aggregation induced by FMLP with or without CB that was significantly increased compared with the cohort of pain-free SCD patients (p less than 0.001).
Positive_regulation (increased) of CB in PMN associated with sickle cell anemia and pain
2) Confidence 0.10 Published 1987 Journal Am. J. Med. Sci. Section Abstract Doc Link 3661621 Disease Relevance 0.96 Pain Relevance 0.35
The latter was preceded by (i) marginal membrane ruffles (DB-cAMP) and (ii) increased zeiotic activity (CB), which were visible within 20 min of the exposure, followed (30-90 min incubation) by a centripetal retraction of the cytoplasm and progressive development of complete or partial arborization.
Spec (partial) Positive_regulation (increased) of CB
3) Confidence 0.05 Published 1989 Journal Cell Tissue Res. Section Abstract Doc Link 2538239 Disease Relevance 0 Pain Relevance 0.28
In addition, repeated treatment with Delta(9)-THC reversed the increase in cerebral blood flow (CBF), while cannabidiol did not reverse that effect.
Positive_regulation (increase) of cerebral blood flow in blood
4) Confidence 0.04 Published 2007 Journal Neuropharmacology Section Abstract Doc Link 17320118 Disease Relevance 0.08 Pain Relevance 0.33
The data demonstrate that the atherogenic diet brings about a significant impairment of CBF; SUL is inactive in normal rabbits, while in the atherosclerotic rabbits it induces a pronounced increase in cerebral blood flow in the grey matter and an enhancement of the corresponding circulatory compartment.
Positive_regulation (increase) of cerebral blood flow in grey matter associated with atherosclerosis
5) Confidence 0.03 Published 1986 Journal Arzneimittelforschung Section Abstract Doc Link 3008769 Disease Relevance 0.10 Pain Relevance 0
In the brain, neuronal activation triggers an increase in cerebral blood flow (CBF).
Positive_regulation (increase) of cerebral blood flow in brain
6) Confidence 0.02 Published 2007 Journal J. Neurosci. Section Abstract Doc Link 17567806 Disease Relevance 0 Pain Relevance 0.19
Administration of the opiate antagonist WIN44,441-3 (with enhanced activity at kappa-receptors) stereospecifically increased cerebral blood flow to the injured regions.
Positive_regulation (increased) of cerebral blood flow in blood associated with antagonist and opiate
7) Confidence 0.01 Published 1986 Journal NIDA Res. Monogr. Section Abstract Doc Link 2893281 Disease Relevance 0.41 Pain Relevance 0.41
During neural activation, brain tissue partial pressure of oxygen (P(O2)) and local cerebral blood flow (CBF) were similarly increased.
Positive_regulation (increased) of cerebral blood flow in blood
8) Confidence 0.01 Published 2009 Journal Adv. Exp. Med. Biol. Section Abstract Doc Link 19227484 Disease Relevance 0.09 Pain Relevance 0.09
Our results suggest that anesthesia-dependent MAP change modulates the apnea-induced cerebral blood flow (CBF) response but has a minimal effect on the fMRI-BOLD signal probably due to uncoupling of CBF and oxygen consumption.
Positive_regulation (induced) of cerebral blood flow in blood associated with anesthesia and sleep disorders
9) Confidence 0.01 Published 2004 Journal Brain Res. Section Abstract Doc Link 15157800 Disease Relevance 0.82 Pain Relevance 0.23
The overall effect of activation of the eCB system in response to ischemia is not yet fully elucidated.
Positive_regulation (activation) of eCB associated with ischemia
10) Confidence 0.01 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2877050 Disease Relevance 0.70 Pain Relevance 0.20
Maintenance of cerebral blood flow and metabolism during pharmacological hypotension in aged hypertensive rats.
Positive_regulation (Maintenance) of cerebral blood flow in blood associated with pressure volume 2 under development and hypertension
11) Confidence 0.01 Published 1982 Journal Neurobiol. Aging Section Title Doc Link 6813750 Disease Relevance 0.90 Pain Relevance 0.10
In the brain, neuronal activation triggers an increase in cerebral blood flow (CBF).
Positive_regulation (increase) of cerebral blood flow in neuronal
12) Confidence 0.01 Published 2007 Journal J. Neurosci. Section Abstract Doc Link 17567806 Disease Relevance 0 Pain Relevance 0.19
In nonhuman primates intracarotid adenosine, but not sodium nitroprusside, increases cerebral blood flow.
Positive_regulation (increases) of cerebral blood flow in blood associated with adenocard
13) Confidence 0.01 Published 2002 Journal Anesth. Analg. Section Title Doc Link 11812706 Disease Relevance 0.16 Pain Relevance 0.40
The authors investigated whether the increase in cerebral blood flow (CBF) when pressure passive following hemorrhage was dependent on the technique used to increase cerebral perfusion pressure (CPP).
Spec (whether) Positive_regulation (increase) of cerebral blood flow in blood associated with cva
14) Confidence 0.01 Published 1989 Journal Anesthesiology Section Abstract Doc Link 2729641 Disease Relevance 0.29 Pain Relevance 0.30
Ketamine does not increase cerebral blood flow velocity or intracranial pressure during isoflurane/nitrous oxide anesthesia in patients undergoing craniotomy.
Neg (not) Positive_regulation (increase) of cerebral blood flow in blood associated with anesthesia, ketamine, isoflurane and cva
15) Confidence 0.01 Published 1995 Journal Anesth. Analg. Section Title Doc Link 7598288 Disease Relevance 0.58 Pain Relevance 0.71
It has been demonstrated in several species that a significant increase in cerebral blood flow (CBF) occurs when nitrous oxide is added to a volatile anaesthetic.
Positive_regulation (increase) of cerebral blood flow in blood
16) Confidence 0.01 Published 1990 Journal Br J Anaesth Section Abstract Doc Link 2223338 Disease Relevance 0 Pain Relevance 0.11
In AD and unrelated tauopathies, cell-cycle events are suggested to correlate with, if not cause neuro-degeneration.
Neg (not) Positive_regulation (cause) of neuro-degeneration associated with tauopathy and disease
17) Confidence 0.00 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2748684 Disease Relevance 0.44 Pain Relevance 0
Cerebral blood flow increased from 37 +/- 3 to 66 +/- 15 mL x 100 g(-1) x min(-1) during hemodilution and returned to baseline after infusion of red blood cells.
Positive_regulation (increased) of Cerebral blood flow in blood
18) Confidence 0.00 Published 2001 Journal J Neurosurg Anesthesiol Section Abstract Doc Link 11145476 Disease Relevance 0.22 Pain Relevance 0
We observed an increase in cerebral blood flow (CBF) for control of pain but were otherwise normal.
Positive_regulation (increase) of cerebral blood flow in blood associated with pain
19) Confidence 0.00 Published 1991 Journal Pacing Clin Electrophysiol Section Abstract Doc Link 1705326 Disease Relevance 0.49 Pain Relevance 0.30
It dilates cephalic arteries without increasing cerebral blood flow (CBF).
Neg (without) Positive_regulation (increasing) of cerebral blood flow in blood
20) Confidence 0.00 Published 2009 Journal Cephalalgia Section Abstract Doc Link 19438913 Disease Relevance 0.41 Pain Relevance 0.41

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox