INT234012

Context Info Confidence 0.02 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.35 Pain Relevance 0

extracellular region (MEPE) proteinaceous extracellular matrix (MEPE)

MEPE (Homo sapiens)

Pain Link Frequency Relevance Heat palliative 1 5.00 Pain 1 5.00 Thoracotomy 1 5.00 abdominal pain 1 5.00 positron emission tomography 1 5.00

Disease Link Frequency Relevance Heat Melanoma 39 99.70 Carcinoma 5 96.04 Metastasis 36 95.66 Cancer 20 88.40 Sarcoma 1 69.20 Lymphatic System Cancer 4 68.76 Freckles 1 37.56 Necrosis 1 37.00 Vomiting 6 5.00 Disease 4 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Thus, a broader panel of immuno-markers may be useful in distinguishing between metastases of malignant melanoma and other metastatic malignancies when the lesion is morphologically undifferentiated; Gupta et al. [15], in fact, reported four cases of morphologically undifferentiated melanoma that showed a positivity for HMB45 (two cases), S100 (one case), vimentin (three cases), NKI/C3 (two cases), NKI/Bteb (one case) and CK (three cases).

HMB45 Binding (positivity) of associated with melanoma, carcinoma and metastasis

1) Confidence 0.02 Published 2008 Journal J Med Case Reports Section Body Doc Link PMC2396655 Disease Relevance 1.35 Pain Relevance 0

General Comments

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