INT23411

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.38
First Reported 1985
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 1.15
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Tnip1) cytoplasm (Tnip1)
Anatomy Link Frequency
neurons 1
trachea 1
Tnip1 (Mus musculus)
Pain Link Frequency Relevance Heat
cocaine 41 97.84 Very High Very High Very High
tetrodotoxin 2 78.28 Quite High
Snapping jaw 2 50.00 Quite Low
Kinase C 7 5.00 Very Low Very Low Very Low
drug abuse 6 5.00 Very Low Very Low Very Low
opiate 3 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Morphine 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dementia 13 99.98 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 99 99.54 Very High Very High Very High
Superinfection 4 99.16 Very High Very High Very High
Temporomandibular Joint Syndrome 2 50.00 Quite Low
Apoptosis 4 15.20 Low Low
Infection 12 5.00 Very Low Very Low Very Low
Drug Dependence 6 5.00 Very Low Very Low Very Low
Motor Neuron Diseases 5 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Cocaine Dependence 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Ouabain completely and VAN partially inhibited this K-induced relaxation.
Negative_regulation (inhibited) of VAN
1) Confidence 0.38 Published 1985 Journal Arch Int Pharmacodyn Ther Section Abstract Doc Link 2413812 Disease Relevance 0 Pain Relevance 0.07
In monkey trachea, however, K-induced contraction was completely inhibited and VAN- and carbachol-induced contractions were partially inhibited by sodium nitroprusside.
Negative_regulation (inhibited) of VAN in trachea
2) Confidence 0.38 Published 1985 Journal Arch Int Pharmacodyn Ther Section Abstract Doc Link 2413812 Disease Relevance 0 Pain Relevance 0.08
Instead, overjet reduction during van Beek activator treatment was found to be due to a favorable dental reaction.


Negative_regulation (reduction) of van Beek activator
3) Confidence 0.31 Published 2007 Journal Angle Orthod Section Body Doc Link 17029547 Disease Relevance 0 Pain Relevance 0
The authors propose that Nef-mediated CXCR4 downregulation may protect against superinfection.
Negative_regulation (downregulation) of Nef-mediated associated with superinfection
4) Confidence 0.07 Published 2008 Journal Virol J Section Body Doc Link PMC2262066 Disease Relevance 0.88 Pain Relevance 0
Cocaine effects may be important in vivo since the neurons of drug abusing patients with HIV-1 associated dementia displayed gp120, p24 and Nef.



Negative_regulation (displayed) of Nef in neurons associated with dementia, acquired immune deficiency syndrome or hiv infection and cocaine
5) Confidence 0.06 Published 2008 Journal The Open Virology Journal Section Abstract Doc Link PMC2678818 Disease Relevance 0.27 Pain Relevance 0.17

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox