INT234164

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.27
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Sod1, Dynll1) cytoplasm (Sod1, Dynll1) cytosol (Sod1, Dynll1)
nucleus (Sod1, Dynll1) transport (Dynll1) aging (Sod1)
Anatomy Link Frequency
motor neurons 3
Sod1 (Mus musculus)
Dynll1 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 9 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Motor Neuron Diseases 30 100.00 Very High Very High Very High
Lifespan 3 88.24 High High
Sprains And Strains 9 59.00 Quite High
Targeted Disruption 6 55.48 Quite High
Disease 3 24.08 Low Low
Death 6 22.16 Low Low
Paralysis 3 21.76 Low Low
Neurodegenerative Disease 9 17.28 Low Low
Movement Disorders 3 6.56 Low Low
Nociception 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Research investigating interactions between cytoplasmic dynein and mutant SOD1 includes reports of co-localization of dynein components and mutant SOD1 in ALS mouse models [17], the interaction of mutant SOD1 proteins with cytoplasmic dynein [18] and perturbation of transport of mitochondria in motor neurons from SOD1G93A mice [19].
SOD1 Binding (interaction) of cytoplasmic dynein in motor neurons associated with motor neuron diseases
1) Confidence 0.06 Published 2008 Journal Genome Biol Section Body Doc Link PMC2397497 Disease Relevance 0.35 Pain Relevance 0
Research investigating interactions between cytoplasmic dynein and mutant SOD1 includes reports of co-localization of dynein components and mutant SOD1 in ALS mouse models [17], the interaction of mutant SOD1 proteins with cytoplasmic dynein [18] and perturbation of transport of mitochondria in motor neurons from SOD1G93A mice [19].
SOD1 Binding (interactions) of cytoplasmic dynein in motor neurons associated with motor neuron diseases
2) Confidence 0.05 Published 2008 Journal Genome Biol Section Body Doc Link PMC2397497 Disease Relevance 0.47 Pain Relevance 0
Research investigating interactions between cytoplasmic dynein and mutant SOD1 includes reports of co-localization of dynein components and mutant SOD1 in ALS mouse models [17], the interaction of mutant SOD1 proteins with cytoplasmic dynein [18] and perturbation of transport of mitochondria in motor neurons from SOD1G93A mice [19].
SOD1 Binding (interaction) of cytoplasmic dynein in motor neurons associated with motor neuron diseases
3) Confidence 0.04 Published 2008 Journal Genome Biol Section Body Doc Link PMC2397497 Disease Relevance 0.46 Pain Relevance 0

General Comments

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