INT234184

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Context Info
Confidence 0.55
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.95
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (PALB2) nucleus (PALB2) DNA binding (PALB2)
PALB2 (Homo sapiens)
Pain Link Frequency Relevance Heat
Chronic pancreatitis 1 67.84 Quite High
imagery 17 5.00 Very Low Very Low Very Low
palliative 2 5.00 Very Low Very Low Very Low
potassium channel 1 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
metalloproteinase 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pancreatic Cancer 36 99.84 Very High Very High Very High
Fanconi Anemia 2 95.04 Very High Very High Very High
Breast Cancer 167 84.56 Quite High
Disease 49 83.20 Quite High
Cancer 104 69.52 Quite High
Pancreatitis 1 67.84 Quite High
Diabetes Mellitus 3 66.80 Quite High
Nicotine Addiction 3 66.24 Quite High
Death 3 38.68 Quite Low
Noninfiltrating Intraductal Carcinoma 21 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The FANCD1, FANCJ and FANCN gene products act downstream of this step.
Gene_expression (products) of FANCN
1) Confidence 0.55 Published 2008 Journal Breast Cancer Res Section Body Doc Link PMC2397525 Disease Relevance 0.60 Pain Relevance 0
In the last decade, the advancement of molecular biology improved the understanding of the pathogenesis of pancreatic cancer and characterized a number of genes that mutated in pancreatic cancers, such as somatic mutations in genes INK4A(CDKN2A), TP53, DPC4, BRCA1/2, STK11, APC, KRAS and ATM and PALB2 are found in pancreatic cancers [10]–[18].
Gene_expression (found) of PALB2 associated with pancreatic cancer
2) Confidence 0.37 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2912284 Disease Relevance 1.35 Pain Relevance 0.07

General Comments

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