INT234196

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Context Info
Confidence 0.19
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.79
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (ERBB2, HSP90AA1) signal transduction (ERBB2, HSP90AA1) plasma membrane (ERBB2, HSP90AA1)
unfolded protein binding (HSP90AA1) small molecule metabolic process (HSP90AA1) intracellular (HSP90AA1)
ERBB2 (Homo sapiens)
HSP90AA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 3 69.20 Quite High
anesthesia 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 53 100.00 Very High Very High Very High
Breast Cancer 36 96.48 Very High Very High Very High
Apoptosis 2 86.08 High High
Shock 8 83.92 Quite High
Body Weight 6 5.00 Very Low Very Low Very Low
Solid Tumor 2 5.00 Very Low Very Low Very Low
Hematologic Neoplasms 2 5.00 Very Low Very Low Very Low
Colon Cancer 2 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, although ERBB2 is an excellent client protein, ERBB2-negative tumors may well be driven by susceptible client proteins and respond to HSP90 inhibitors.
ERBB2 Positive_regulation (respond) of Negative_regulation (inhibitors) of HSP90 associated with cancer
1) Confidence 0.19 Published 2008 Journal Breast Cancer Res Section Body Doc Link PMC2397535 Disease Relevance 0.79 Pain Relevance 0.03

General Comments

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