INT23420

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Context Info
Confidence 0.49
First Reported 1985
Last Reported 2009
Negated 0
Speculated 1
Reported most in Abstract
Documents 8
Total Number 9
Disease Relevance 4.81
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Spn)
Anatomy Link Frequency
SPN 1
SPN 1
sympathetic 1
duodenum 1
T-cell 1
Spn (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Spinal cord 3 100.00 Very High Very High Very High
Neurolysis 1 99.20 Very High Very High Very High
Neurotransmitter 3 89.76 High High
Pain 2 88.16 High High
abdominal pain 2 78.12 Quite High
imagery 1 76.92 Quite High
headache 1 74.20 Quite High
Serotonin 1 51.04 Quite High
substance P 3 50.16 Quite High
Morphine 4 50.00 Quite Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 32 100.00 Very High Very High Very High
Neuroma 1 98.72 Very High Very High Very High
Cancer 6 98.40 Very High Very High Very High
Pressure Volume 2 Under Development 6 95.92 Very High Very High Very High
Hematological Disease 2 88.24 High High
Pain 2 88.16 High High
Plasmacytoma 4 85.96 High High
Splenomegaly 1 85.08 High High
Anaemia 2 83.44 Quite High
Breast Cancer 1 83.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Many other cells were positive for CD43 antibody staining, indicating that the tumor was hematopoietic in nature, so-called sclerosing extramedullary hematopoietic tumor.
Positive_regulation (positive) of CD43 associated with cancer
1) Confidence 0.49 Published 2002 Journal Ann Diagn Pathol Section Abstract Doc Link 12089730 Disease Relevance 1.45 Pain Relevance 0.08
Awareness of this unusual variant location will enable the surgeon to find and preserve the SPN during fasciotomy, neurolysis, neuroma resection, or bony and soft tissue reconstruction.
Spec (find) Positive_regulation (preserve) of SPN in SPN associated with neurolysis, neuroma and urological neuroanatomy
2) Confidence 0.39 Published 2007 Journal Microsurgery Section Abstract Doc Link 17596897 Disease Relevance 0.74 Pain Relevance 0.17
Sympathetic preganglionic neurons (SPN) in rat spinal cord were activated by the reflex stimulation of bulbospinal sympathetic neuronal pathways after a nitroprusside-induced hypotension.
Positive_regulation (activated) of SPN in sympathetic associated with pressure volume 2 under development, urological neuroanatomy and spinal cord
3) Confidence 0.34 Published 2002 Journal J. Comp. Neurol. Section Abstract Doc Link 12115667 Disease Relevance 0.71 Pain Relevance 0.13
But CCK-8 could selectively antagonize the effects of morphine, ie, the SPA and SPN were increased again, followed by an increase of CA.
Positive_regulation (increased) of SPN
4) Confidence 0.27 Published 2002 Journal Acta Pharmacol. Sin. Section Body Doc Link 12100748 Disease Relevance 0 Pain Relevance 0
RESULTS: Acetylcholine (ACh, 300 nmol/L) increased the spike potential amplitude (SPA) and the number (SPN) of rat duodenum in vitro, followed by an increase of duodenal contraction amplitudes (CA).
Positive_regulation (increased) of SPN in duodenum
5) Confidence 0.27 Published 2002 Journal Acta Pharmacol. Sin. Section Body Doc Link 12100748 Disease Relevance 0 Pain Relevance 0
All cases were positive for CD20 and BCL2 and negative for CD3, CD5, CD23, CD43, and cyclin D1.
Positive_regulation (negative) of CD43
6) Confidence 0.03 Published 2002 Journal Am. J. Surg. Pathol. Section Abstract Doc Link 11812943 Disease Relevance 0.45 Pain Relevance 0.07
Immunohistochemical staining was positive for CD45 (LCA), CD56 (N-CAM), CD43 (MT1), and cytokeratin CAM5.2.
Positive_regulation (positive) of CD43
7) Confidence 0.02 Published 2001 Journal J. Histochem. Cytochem. Section Abstract Doc Link 11373326 Disease Relevance 0.47 Pain Relevance 0.09
These results suggest that the innervation of visceral organs is not obviously peptide-specific, although some organs may be innervated by a greater proportion of SPN containing one of these peptides.
Positive_regulation (proportion) of SPN in SPN associated with urological neuroanatomy
8) Confidence 0.02 Published 1985 Journal J. Comp. Neurol. Section Abstract Doc Link 2414342 Disease Relevance 0.76 Pain Relevance 0.04
Immunoperoxidase stains performed on the cell block/core specimen showed that the large atypical cells were positive for CD2, CD30, CD43 and CD56, TIA-1, granzyme, and perforin, but for none of the other T-cell markers used (CD3, CD4, CD5, CD8, CD45RO), which stained the abundant background lymphocytes.
Positive_regulation (positive) of CD43 in T-cell
9) Confidence 0.01 Published 2009 Journal Diagn. Cytopathol. Section Abstract Doc Link 19373919 Disease Relevance 0.21 Pain Relevance 0.11

General Comments

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