INT234215

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.17
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (HSP90AA1, Tpt1, HSP90AA1) unfolded protein binding (HSP90AA1, HSP90AA1) small molecule metabolic process (HSP90AA1, HSP90AA1)
intracellular (HSP90AA1, HSP90AA1) response to stress (HSP90AA1, HSP90AA1) cytosol (HSP90AA1, HSP90AA1)
HSP90AA1 (Homo sapiens)
Tpt1 (Mus musculus)
HSP90AA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Potency 3 18.08 Low Low
anesthesia 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 53 61.68 Quite High
Breast Cancer 36 55.12 Quite High
Shock 8 5.00 Very Low Very Low Very Low
Body Weight 6 5.00 Very Low Very Low Very Low
Solid Tumor 2 5.00 Very Low Very Low Very Low
Apoptosis 2 5.00 Very Low Very Low Very Low
Hematologic Neoplasms 2 5.00 Very Low Very Low Very Low
Colon Cancer 2 5.00 Very Low Very Low Very Low
Hyperplasia 1 5.00 Very Low Very Low Very Low
Toxicity 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HSP90 recruits various cochaperones at different points in its catalytic cycle, and the association of HSP90 with p23 is essential for HSP90 activity and client protein stability.
HSP90 Binding (association) of p23 Positive_regulation (essential) of HSP90
1) Confidence 0.03 Published 2008 Journal Breast Cancer Res Section Body Doc Link PMC2397535 Disease Relevance 0.17 Pain Relevance 0

General Comments

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