INT234257

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.44
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 1.98
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (PSEN1) Golgi apparatus (PSEN1) endoplasmic reticulum (PSEN1)
embryo development (PSEN1) peptidase activity (PSEN1) cell death (PSEN1)
Anatomy Link Frequency
cleavage 2
fibroblasts 2
PSEN1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 35 99.56 Very High Very High Very High
Potency 8 93.48 High High
bradykinin 75 45.20 Quite Low
aspirin 12 39.92 Quite Low
Eae 3 9.24 Low Low
Inflammation 31 5.00 Very Low Very Low Very Low
Central nervous system 5 5.00 Very Low Very Low Very Low
ischemia 5 5.00 Very Low Very Low Very Low
Peripheral nervous system 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Generaliased Trisomy 2 100.00 Very High Very High Very High
Syndrome 15 99.60 Very High Very High Very High
Disease 382 99.36 Very High Very High Very High
Death 9 80.64 Quite High
Amyloid Plaque 11 76.32 Quite High
Congenital Anomalies 3 73.32 Quite High
Aging 5 60.56 Quite High
Toxicity 19 53.88 Quite High
Disorder Of Lipid Metabolism 1 52.64 Quite High
Stress 128 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
DownÂ’s syndrome (DS) patients, who are trisomic for chromosome 21 and thus have an extra copy of the APP gene, and FAD families with a duplicated APP gene locus [4] exhibit total A?
Regulation (trisomic) of Gene_expression (families) of FAD associated with syndrome and generaliased trisomy
1) Confidence 0.44 Published 2007 Journal Current Genomics Section Body Doc Link PMC2647160 Disease Relevance 1.43 Pain Relevance 0
Differential effects on Notch S3-cleavage in PS1 mutants
Regulation (cleavage) of Gene_expression (mutants) of PS1 in cleavage
2) Confidence 0.37 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2405781 Disease Relevance 0 Pain Relevance 0.09
Consistently, PS1-D257TG and PS1-D385TG mutants were also affected differently by ?
Regulation (affected) of Gene_expression (mutants) of PS1-D385TG
3) Confidence 0.37 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2405781 Disease Relevance 0 Pain Relevance 0
NSAIDs display differential effects on PS1 mutants
Regulation (effects) of Gene_expression (mutants) of PS1 associated with cinod
4) Confidence 0.37 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2405781 Disease Relevance 0.05 Pain Relevance 0.33
Consistently, PS1-D257TG and PS1-D385TG mutants were also affected differently by ?
Regulation (affected) of Gene_expression (mutants) of PS1-D257TG
5) Confidence 0.37 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2405781 Disease Relevance 0 Pain Relevance 0
PS-1 M146L AD has one of the earlier ages of onset among PS-1 mutations, occurring below age 40, and skin fibroblasts from such individuals elaborate a 9-fold greater amount of A?
Regulation (onset) of Gene_expression (mutations) of PS-1 in fibroblasts associated with disease
6) Confidence 0.33 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2644820 Disease Relevance 0.49 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox