INT234303

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Context Info
Confidence 0.36
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Gria3, Gria4) plasma membrane (Gria3, Gria4) protein complex (Gria3)
Anatomy Link Frequency
thalamus 1
Gria3 (Mus musculus)
Gria4 (Mus musculus)
Pain Link Frequency Relevance Heat
Thalamus 13 99.96 Very High Very High Very High
cerebral cortex 4 58.80 Quite High
Glutamate receptor 4 5.00 Very Low Very Low Very Low
Action potential 4 5.00 Very Low Very Low Very Low
midbrain 2 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
tetrodotoxin 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
GABA receptor 1 5.00 Very Low Very Low Very Low
sodium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Absence Epilepsy 15 50.00 Quite Low
Targeted Disruption 9 50.00 Quite Low
Sprains And Strains 20 48.40 Quite Low
Ataxia 5 21.04 Low Low
Convulsion 5 5.00 Very Low Very Low Very Low
Epilepsy 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Generalized Epilepsy 2 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As GluR4 containing AMPA receptors express fast decay kinetics, e.g. compared with the other subunit expressed in the reticular thalamus, GluR3 (22,23), then loss of GluR4 would be expected to increase the duration of the excitatory synaptic responses, consistent with our observations.
GluR3 Negative_regulation (loss) of GluR4 in thalamus associated with thalamus
1) Confidence 0.36 Published 2008 Journal Human Molecular Genetics Section Body Doc Link PMC2405903 Disease Relevance 0 Pain Relevance 0.16

General Comments

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