INT234423

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Context Info
Confidence 0.07
First Reported 2008
Last Reported 2010
Negated 2
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 3.03
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (CASP8) peptidase activity (CASP8) mitochondrion (CASP8)
nucleolus (CASP8) cytoskeleton (CASP8) nucleus (CASP8)
CASP8 (Homo sapiens)
Pain Link Frequency Relevance Heat
palliative 2 16.40 Low Low
agonist 11 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
antagonist 4 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
chemokine 1 5.00 Very Low Very Low Very Low
Multiple sclerosis 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 203 95.68 Very High Very High Very High
Chronic Lymphoid Leukemia 14 92.56 High High
Parkinson's Disease 2 84.96 Quite High
Leukemia 54 71.72 Quite High
Disease 9 65.68 Quite High
Diffuse Large B-cell Lymphoma 11 63.96 Quite High
B-cell Lymphoma 2 63.68 Quite High
Lymphatic System Cancer 25 56.48 Quite High
Cancer 54 50.08 Quite High
Mantle-cell Lymphoma 1 48.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
affected the levels of an endogenous caspase-8 inhibitor, c-FLIP (caspase-8
Regulation (affected) of Gene_expression (levels) of caspase-8
1) Confidence 0.07 Published 2008 Journal PPAR Research Section Body Doc Link PMC2408681 Disease Relevance 1.52 Pain Relevance 0
The expression levels of pro-caspase-8 were not changed after NCTD treatment (Figure 6B).
Neg (not) Regulation (changed) of Gene_expression (expression) of pro-caspase-8
2) Confidence 0.04 Published 2010 Journal J Exp Clin Cancer Res Section Body Doc Link PMC2987898 Disease Relevance 0.91 Pain Relevance 0
The expression levels of pro-caspase-8 were not changed after NCTD treatment.


Neg (not) Regulation (changed) of Gene_expression (expression) of pro-caspase-8
3) Confidence 0.02 Published 2010 Journal J Exp Clin Cancer Res Section Abstract Doc Link PMC2987898 Disease Relevance 0.61 Pain Relevance 0

General Comments

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