INT234454

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.18
First Reported 2006
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 8.30
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
liver 2
HCC (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 8 59.88 Quite High
Inflammation 20 50.00 Quite Low
fibrosis 25 27.36 Quite Low
cytokine 20 14.84 Low Low
agonist 20 5.00 Very Low Very Low Very Low
Bile 7 5.00 Very Low Very Low Very Low
alcohol 6 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Familial Adenomatous Polyposis 312 100.00 Very High Very High Very High
Hepatocellular Cancer 257 100.00 Very High Very High Very High
Carcinoma 17 100.00 Very High Very High Very High
Cancer 216 99.64 Very High Very High Very High
Liver Cancer 43 99.12 Very High Very High Very High
Hepatitis Virus Infection 12 90.36 High High
Hemorrhage 1 84.08 Quite High
Liver Disease 2 74.64 Quite High
Hepatitis 19 73.44 Quite High
Cirrhosis 58 72.32 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
in both human HCC tissues and a human HCC cell line, whereas RXR?
Regulation (human) of Gene_expression (tissues) of HCC associated with carcinoma
1) Confidence 0.18 Published 2008 Journal PPAR Research Section Body Doc Link PMC2408709 Disease Relevance 0.75 Pain Relevance 0
Because promoter methylation is significantly enhanced in HCC compared to that of non-tumor samples, and APC expression is also significantly reduced in liver cancer cells, higher degrees of promoter methylation of the APC gene seem to be responsible for the reduced APC protein expression in HCC.
Regulation (responsible) of Gene_expression (expression) of HCC in liver associated with liver cancer, cancer, familial adenomatous polyposis and hepatocellular cancer
2) Confidence 0.12 Published 2007 Journal J Cancer Res Clin Oncol Section Body Doc Link PMC2757596 Disease Relevance 1.77 Pain Relevance 0
Previous studies focused on epigenetic changes of the APC promoter but did not evaluate the APC protein expression in HCC (Lee et al. 2003; Yang et al. 2003; Esteller et al. 2001; Yu et al. 2002).
Neg (not) Regulation (evaluate) of Gene_expression (expression) of HCC associated with hepatocellular cancer and familial adenomatous polyposis
3) Confidence 0.12 Published 2007 Journal J Cancer Res Clin Oncol Section Body Doc Link PMC2757596 Disease Relevance 1.81 Pain Relevance 0
Therefore, in our analysis, we assessed the impact of promoter methylation of APC on protein expression in HCC and non-tumor tissue samples.
Regulation (impact) of Gene_expression (expression) of HCC associated with cancer, hepatocellular cancer and familial adenomatous polyposis
4) Confidence 0.12 Published 2007 Journal J Cancer Res Clin Oncol Section Body Doc Link PMC2757596 Disease Relevance 2.03 Pain Relevance 0
All previous studies have reported different prognostic factors affecting the long term survival after HCC resection.
Regulation (affecting) of Gene_expression (resection) of HCC associated with hepatocellular cancer
5) Confidence 0.11 Published 2006 Journal Yonsei Medical Journal Section Body Doc Link PMC2687566 Disease Relevance 0.62 Pain Relevance 0.06
Antioxidants role in HCC chemoprevention
Regulation (role) of Gene_expression (chemoprevention) of HCC associated with hepatocellular cancer
6) Confidence 0.07 Published 2010 Journal J Transl Med Section Body Doc Link PMC2991329 Disease Relevance 1.33 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox