INT234469

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Context Info
Confidence 0.14
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.25
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (NR1H4) signal transduction (NR1H4) nucleus (NR1H4)
NR1H4 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 20 93.04 High High
Inflammation 2 5.00 Very Low Very Low Very Low
headache 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 43 98.32 Very High Very High Very High
Apoptosis 58 96.40 Very High Very High Very High
Toxicity 6 86.84 High High
Cancer 45 77.92 Quite High
Breast Cancer 42 68.68 Quite High
Liposarcoma 4 58.72 Quite High
Disease 13 32.84 Quite Low
Colon Cancer 19 5.00 Very Low Very Low Very Low
Carcinoma 14 5.00 Very Low Very Low Very Low
Leukemia 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, phosphorylation of RXR?
Negative_regulation (However) of Phosphorylation (phosphorylation) of RXR
1) Confidence 0.14 Published 2008 Journal PPAR Research Section Body Doc Link PMC2408709 Disease Relevance 0.27 Pain Relevance 0.12
A recent study reported synergistic growth inhibition and induction of apoptosis for the combination of trastuzumab and 9-cis-RA in hepatocellular cells [59], suggesting application to a broader range of malignancies; that report demonstrated that trastuzumab inhibited phosphorylation of RXR?
Negative_regulation (inhibited) of Phosphorylation (phosphorylation) of RXR associated with rheumatoid arthritis and apoptosis
2) Confidence 0.02 Published 2010 Journal Breast Cancer Res Section Body Doc Link PMC2949655 Disease Relevance 0.98 Pain Relevance 0.04

General Comments

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