INT234592

Context Info Confidence 0.36 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.11 Pain Relevance 0.10

cytosol (Ncf2) nucleolus (Ncf2) cytoplasm (Ncf2)

Ncf2 (Mus musculus)

Pain Link Frequency Relevance Heat COX-2 inhibitor 4 73.36 cytokine 19 65.04 Inflammation 21 57.60 Inflammatory response 6 47.52 Inflammatory mediators 3 36.60 Central nervous system 8 5.00 chemokine 8 5.00 cINOD 4 5.00 Intracerebroventricular 3 5.00 Inflammatory stimuli 3 5.00

Disease Link Frequency Relevance Heat INFLAMMATION 35 57.60 Stress 3 51.04 Neurodegenerative Disease 3 5.00 Injury 3 5.00 Drug Induced Neurotoxicity 3 5.00 Disease 3 5.00 Death 2 5.00 Necrosis 2 5.00 Cognitive Disorder 2 5.00 Sprains And Strains 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The protein levels of p67phox (Fig. 7C and 7D) and phosphorylated STAT3 after LPS (Fig. 7E and 7F) were also higher in the celecoxib-treated mice compared to untreated mice.

Positive_regulation (higher) of Gene_expression (levels) of p67phox

1) Confidence 0.36 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2409311 Disease Relevance 0.11 Pain Relevance 0.10

General Comments

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