INT234600

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.60
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Cpox, Ptgds) isomerase activity (Ptgds) transport (Ptgds)
mitochondrion (Cpox) Golgi apparatus (Ptgds) endoplasmic reticulum (Ptgds)
Cpox (Mus musculus)
Ptgds (Mus musculus)
Pain Link Frequency Relevance Heat
COX-2 inhibitor 4 100.00 Very High Very High Very High
Inflammation 21 98.56 Very High Very High Very High
Paracetamol 1 64.88 Quite High
cytokine 19 60.00 Quite High
chemokine 8 58.88 Quite High
Inflammatory response 6 53.20 Quite High
Multiple sclerosis 1 35.84 Quite Low
rheumatoid arthritis 1 25.20 Quite Low
Central nervous system 8 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 35 98.56 Very High Very High Very High
Hepatotoxicity 1 65.80 Quite High
Ocular & Orbital Inflammation 1 62.88 Quite High
Convulsion 1 58.20 Quite High
Drug Induced Neurotoxicity 3 46.64 Quite Low
Parkinson's Disease 1 41.08 Quite Low
Neurological Disease 1 38.48 Quite Low
Demyelinating Disease 1 35.84 Quite Low
Disease 3 32.96 Quite Low
Familial Adenomatous Polyposis 1 26.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, Gilroy and colleagues demonstrated that selective COX-2 inhibitors, by blocking the production of PGE2 and PGD2, disturbed the resolution phase of inflammation, leading to delay in return to homeostasis [50].
Negative_regulation (inhibitors) of COX Negative_regulation (blocking) of Gene_expression (production) of PGD2 associated with inflammation and cox-2 inhibitor
1) Confidence 0.05 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2409311 Disease Relevance 0.60 Pain Relevance 0.44

General Comments

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