INT234608

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.54
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Socs3) endoplasmic reticulum (SOAT1) transferase activity, transferring acyl groups (SOAT1)
cytoplasm (Socs3)
Socs3 (Mus musculus)
SOAT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 19 99.92 Very High Very High Very High
Inflammatory mediators 3 84.96 Quite High
Inflammation 21 74.76 Quite High
chemokine 8 52.40 Quite High
Multiple sclerosis 1 49.72 Quite Low
Inflammatory stimuli 3 49.60 Quite Low
COX-2 inhibitor 4 15.12 Low Low
cINOD 4 7.12 Low Low
Central nervous system 8 5.00 Very Low Very Low Very Low
Inflammatory response 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 35 84.56 Quite High
Drug Induced Neurotoxicity 3 78.44 Quite High
Disease 3 50.72 Quite High
Demyelinating Disease 1 49.72 Quite Low
Neurological Disease 1 48.56 Quite Low
Neuroblastoma 1 27.92 Quite Low
Death 2 26.40 Quite Low
Neurodegenerative Disease 3 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low
Stress 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SOCS3 is a potent inhibitor of the JAK/STAT signaling cascade, negatively regulating signal transduction pathways mediated by a variety of cytokines.
SOCS3 Negative_regulation (inhibitor) of STAT associated with cytokine
1) Confidence 0.01 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2409311 Disease Relevance 0.54 Pain Relevance 0.39

General Comments

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