INT234621

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Context Info
Confidence 0.38
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.80
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (CDX2, IGFBP3) extracellular space (IGFBP3) extracellular region (IGFBP3)
Anatomy Link Frequency
colon 1
CDX2 (Homo sapiens)
IGFBP3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bioavailability 4 15.44 Low Low
alcohol 3 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adenoma 47 95.64 Very High Very High Very High
Cancer 12 89.44 High High
Malignant Neoplastic Disease 5 77.24 Quite High
Apoptosis 68 68.64 Quite High
Reprotox - General 1 1 60.28 Quite High
Stomach Cancer 1 59.32 Quite High
Colon Cancer 15 13.24 Low Low
Obesity 4 5.00 Very Low Very Low Very Low
Adenomatous Polyps 2 5.00 Very Low Very Low Very Low
Nicotine Addiction 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A recent study reported CDX2 as a transcriptional repressor of IGFBP-3, [40] accordingly, it is possible that CDX2 and other factors interact with IGFBP-3 in the colon to promote adenoma development.
CDX2 Negative_regulation (repressor) of IGFBP-3 in colon associated with adenoma
1) Confidence 0.38 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2409350 Disease Relevance 0.80 Pain Relevance 0

General Comments

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