INT234623

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Context Info
Confidence 0.32
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.71
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (CDX2, IGFBP3) extracellular space (IGFBP3) extracellular region (IGFBP3)
Anatomy Link Frequency
colon 1
CDX2 (Homo sapiens)
IGFBP3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bioavailability 8 22.20 Low Low
alcohol 6 5.00 Very Low Very Low Very Low
cINOD 2 5.00 Very Low Very Low Very Low
Crohn's disease 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adenoma 94 99.00 Very High Very High Very High
Cancer 24 96.20 Very High Very High Very High
Malignant Neoplastic Disease 10 84.00 Quite High
Apoptosis 136 75.36 Quite High
Reprotox - General 1 2 67.04 Quite High
Stomach Cancer 2 66.08 Quite High
Colon Cancer 30 20.00 Low Low
Obesity 8 5.00 Very Low Very Low Very Low
Adenomatous Polyps 4 5.00 Very Low Very Low Very Low
Nicotine Addiction 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A recent study reported CDX2 as a transcriptional repressor of IGFBP-3, [40] accordingly, it is possible that CDX2 and other factors interact with IGFBP-3 in the colon to promote adenoma development.
CDX2 Binding (interact) of IGFBP-3 in colon associated with adenoma
1) Confidence 0.32 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2409350 Disease Relevance 0.79 Pain Relevance 0
and CDX2 interact with IGFBP-3 to mediate its actions [40-42].
CDX2 Binding (interact) of IGFBP-3
2) Confidence 0.32 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2409350 Disease Relevance 0.91 Pain Relevance 0

General Comments

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