INT234625

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Context Info
Confidence 0.29
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.74
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (TP53, IGFBP3) cell differentiation (TP53) nucleoplasm (TP53)
mitochondrion (TP53) DNA binding (TP53) extracellular space (IGFBP3)
Anatomy Link Frequency
colon 1
TP53 (Homo sapiens)
IGFBP3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Bioavailability 4 68.44 Quite High
alcohol 3 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 15 99.84 Very High Very High Very High
Apoptosis 68 96.52 Very High Very High Very High
Malignant Neoplastic Disease 5 55.88 Quite High
Adenoma 47 47.92 Quite Low
Cancer 12 6.88 Low Low
Obesity 4 5.00 Very Low Very Low Very Low
Adenomatous Polyps 2 5.00 Very Low Very Low Very Low
Reprotox - General 1 1 5.00 Very Low Very Low Very Low
Stomach Cancer 1 5.00 Very Low Very Low Very Low
Nicotine Addiction 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IGFBP-3 is induced by p53 in colon cancer cell lines and is thought to play a role in anti-proliferative or pro-apoptotic actions of p53 [12].
p53 Positive_regulation (induced) of IGFBP-3 in colon associated with colon cancer and apoptosis
1) Confidence 0.29 Published 2008 Journal BMC Cancer Section Body Doc Link PMC2409350 Disease Relevance 0.74 Pain Relevance 0.03

General Comments

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