INT234868

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.83
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Dsp) structural molecule activity (Dsp) cytoskeleton (Dsp)
protein binding, bridging (Dsp) cytoplasm (Dsp)
Dsp (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 13 44.08 Quite Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 51 99.96 Very High Very High Very High
Bullous Skin Disease 304 98.10 Very High Very High Very High
Acantholysis 65 97.84 Very High Very High Very High
Stress 4 51.20 Quite High
Apoptosis 19 5.00 Very Low Very Low Very Low
Disease 18 5.00 Very Low Very Low Very Low
Blister 12 5.00 Very Low Very Low Very Low
Vohwinkel Syndrome 6 5.00 Very Low Very Low Very Low
Skin Diseases 5 5.00 Very Low Very Low Very Low
Heart Defects 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The second goal is to characterize whether acantholysis in pemphigus is caused by mechanisms directly targeting desmosomes or whether cellular signalling pathways regulate desmosomal adhesion via reorganisation of the cytoskeleton or via other types of cell contacts such as adherens junctions.



Spec (whether) Regulation (regulate) of desmosomal associated with acantholysis, bullous skin disease and adhesions
1) Confidence 0.02 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2413110 Disease Relevance 0.83 Pain Relevance 0

General Comments

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