INT234873

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.20
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Dsc2) plasma membrane (Dsc2)
Anatomy Link Frequency
myocardium 1
Dsc2 (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 2 6.72 Low Low
Kinase C 13 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Heart Defects 4 98.44 Very High Very High Very High
Disease 18 85.92 High High
Cancer 3 84.32 Quite High
Breast Cancer 1 79.80 Quite High
Skin Cancer 1 77.68 Quite High
Carcinoma 1 76.40 Quite High
Alopecia 2 75.28 Quite High
Bullous Skin Disease 304 71.28 Quite High
Autoimmune Disease 4 70.88 Quite High
Arrhythmogenic Right Ventricular Dysplasia 3 59.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, genetic alterations of Dsg 2, Dsc 2 and plakophilin 2 selectively lead to heart defects because these are the only isoforms of their protein families in the myocardium.
Regulation (alterations) of Dsc 2 in myocardium associated with heart defects
1) Confidence 0.08 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2413110 Disease Relevance 1.20 Pain Relevance 0

General Comments

This test has worked.

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