INT234916

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.25
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

histone binding (Lef1) nucleus (Lef1) DNA binding (Lef1)
transcription factor binding (Lef1) cytoplasm (Lef1)
Anatomy Link Frequency
epithelial cells 1
Lef1 (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 13 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 2 74.80 Quite High
Embryonic Lethality 3 63.08 Quite High
Apoptosis 19 61.52 Quite High
Adhesions 51 40.00 Quite Low
Cancer 3 33.92 Quite Low
Bullous Skin Disease 304 5.00 Very Low Very Low Very Low
Acantholysis 65 5.00 Very Low Very Low Very Low
Disease 18 5.00 Very Low Very Low Very Low
Blister 12 5.00 Very Low Very Low Very Low
Vohwinkel Syndrome 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A target gene of Lef-1/plakoglobin signalling is c-Myc, the expression of which was inhibited in keratinocytes but enhanced in transformed rat kidney epithelial cells (Kolligs et al. 2000; Kolly et al. 2007; Williamson et al. 2006).
Gene_expression (signalling) of Lef-1 in epithelial cells
1) Confidence 0.04 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2413110 Disease Relevance 0.25 Pain Relevance 0

General Comments

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