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Context Info
Confidence 0.21
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.29
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (DSG1) plasma membrane (DSG1)
Anatomy Link Frequency
myocardium 1
dentine 1
DSG1 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 2 6.72 Low Low
Kinase C 13 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Dentinogenesis Imperfecta 86 100.00 Very High Very High Very High
Heart Defects 4 98.08 Very High Very High Very High
Amelogenesis Imperfecta 2 93.68 High High
Cleidocranial Dysplasia 57 89.92 High High
Erythropoietic Porphyria 2 88.00 High High
Disease 23 85.92 High High
Cancer 3 84.32 Quite High
Breast Cancer 1 79.80 Quite High
Skin Cancer 1 77.68 Quite High
Hemolytic Anemia 1 77.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Unlike DGI the teeth are usually sensitive and on radiographs enamel is less radio-dense than dentine [9].
Regulation (sensitive) of DGI in dentine associated with dentinogenesis imperfecta
1) Confidence 0.21 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2600777 Disease Relevance 1.15 Pain Relevance 0
In contrast, genetic alterations of Dsg 2, Dsc 2 and plakophilin 2 selectively lead to heart defects because these are the only isoforms of their protein families in the myocardium.
Regulation (alterations) of Dsg in myocardium associated with heart defects
2) Confidence 0.13 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2413110 Disease Relevance 1.14 Pain Relevance 0

General Comments

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