INT234942

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.14
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (CDH16) plasma membrane (CDH16)
Anatomy Link Frequency
keratinocyte 1
CDH16 (Homo sapiens)
Pain Link Frequency Relevance Heat
Kinase C 13 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Acantholysis 65 97.24 Very High Very High Very High
Bullous Skin Disease 304 89.84 High High
Adhesions 51 70.20 Quite High
Blister 12 65.28 Quite High
Stress 4 29.60 Quite Low
Apoptosis 19 5.00 Very Low Very Low Very Low
Disease 18 5.00 Very Low Very Low Very Low
Vohwinkel Syndrome 6 5.00 Very Low Very Low Very Low
Skin Diseases 5 5.00 Very Low Very Low Very Low
Heart Defects 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Moreover, low temperature-abrogated keratinocyte dissociation but not antibody binding to the keratinocyte cell surface indicating that direct inhibition of cadherin transinteraction by autoantibody binding is not sufficient to cause acantholysis (Calkins et al. 2006).
Negative_regulation (inhibition) of cadherin in keratinocyte associated with acantholysis
1) Confidence 0.01 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2413110 Disease Relevance 1.14 Pain Relevance 0

General Comments

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