INT234978

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.32
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Dsg3, Inppl1) plasma membrane (Dsg3, Inppl1) Golgi apparatus (Inppl1)
cytoskeleton (Inppl1) cytoplasm (Inppl1)
Anatomy Link Frequency
epidermis 2
Dsg3 (Mus musculus)
Inppl1 (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 2 68.68 Quite High
Kinase C 13 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bullous Skin Disease 304 90.32 High High
Disease 18 77.36 Quite High
Adhesions 51 71.68 Quite High
Autoimmune Disease 4 46.32 Quite Low
Carcinoma 1 34.64 Quite Low
Skin Cancer 1 33.12 Quite Low
Breast Cancer 1 28.40 Quite Low
Cancer 3 18.48 Low Low
Darier's Disease 1 16.52 Low Low
Acantholysis 65 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
According to this concept, in healthy epidermis Dsg 3 binding results in inhibition of glycogen synthase kinase 3 (GSK3) via activation of phosphatidylinositol trisphosphate kinase (PI3K) and Akt.
Dsg 3 Binding (binding) of in epidermis Positive_regulation (activation) of phosphatidylinositol trisphosphate kinase
1) Confidence 0.00 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2413110 Disease Relevance 0.32 Pain Relevance 0.03

General Comments

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