INT234983

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell morphogenesis (Jup) cytoplasm (Jup) cytosol (Jup)
structural molecule activity (Jup) cell adhesion (Jup) nucleus (Jup)
IgG (Mus musculus)
Jup (Mus musculus)
Pain Link Frequency Relevance Heat
Kinase C 13 5.00 Very Low Very Low Very Low
metalloproteinase 6 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
addiction 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bullous Skin Disease 304 99.98 Very High Very High Very High
Acantholysis 65 85.16 High High
Disease 18 57.24 Quite High
Apoptosis 19 54.00 Quite High
Adhesions 51 31.20 Quite Low
Blister 12 5.00 Very Low Very Low Very Low
Vohwinkel Syndrome 6 5.00 Very Low Very Low Very Low
Skin Diseases 5 5.00 Very Low Very Low Very Low
Heart Defects 4 5.00 Very Low Very Low Very Low
Skin Infection 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Within 30–60 min, PV-IgG induced internalization and lysosomal degradation of cytoskeleton-unbound Dsg 3 together with plakoglobin (Aoyama and Kitajima 1999; Aoyama et al. 1999; Calkins et al. 2006; Sato et al. 2000; Williamson et al. 2006; Yamamoto et al. 2007a).
IgG Positive_regulation (induced) of Protein_catabolism (degradation) of plakoglobin associated with bullous skin disease
1) Confidence 0.03 Published 2008 Journal Histochem Cell Biol Section Body Doc Link PMC2413110 Disease Relevance 0.61 Pain Relevance 0

General Comments

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