INT235090

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Context Info
Confidence 0.42
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.81
Pain Relevance 0.49

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (NOS1) oxidoreductase activity (NOS1) cytoskeleton (NOS1)
plasma membrane (GRIN1) cytoplasm (NOS1)
GRIN1 (Homo sapiens)
NOS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
nMDA receptor 30 100.00 Very High Very High Very High
Glutamate 39 88.24 High High
Hippocampus 27 72.80 Quite High
Glutamate receptor 3 72.04 Quite High
Inflammation 2 50.00 Quite Low
agonist 1 17.28 Low Low
gABA 28 5.00 Very Low Very Low Very Low
5HT 13 5.00 Very Low Very Low Very Low
long-term potentiation 10 5.00 Very Low Very Low Very Low
depression 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Post-traumatic Stress Disorder 88 98.36 Very High Very High Very High
Stress 82 98.00 Very High Very High Very High
Traumatic Stress Disorders 5 50.00 Quite Low
INFLAMMATION 2 50.00 Quite Low
Injury 25 33.96 Quite Low
Cognitive Disorder 9 7.52 Low Low
Anxiety Disorder 22 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 7 5.00 Very Low Very Low Very Low
Depression 6 5.00 Very Low Very Low Very Low
Frailty 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Glutamatergic stimulation of NMDA receptors activates a number of enzymes including NOS, cyclooxygenases, proteases, lipases, and protein kinases by evoking a long-lasting (100 millisecond) Ca2+-ion influx.
Positive_regulation (stimulation) of NMDA Positive_regulation (activates) of NOS associated with nmda receptor
1) Confidence 0.42 Published 2005 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2413191 Disease Relevance 0.81 Pain Relevance 0.49

General Comments

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