INT235154

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Context Info
Confidence 0.24
First Reported 2005
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.38
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ep300) transferase activity, transferring acyl groups (Ep300) DNA binding (Ep300)
transcription factor binding (Ep300) cytoplasm (Ep300)
Ep300 (Mus musculus)
Pain Link Frequency Relevance Heat
Calcium channel 5 30.56 Quite Low
Inflammation 3 5.00 Very Low Very Low Very Low
Bioavailability 2 5.00 Very Low Very Low Very Low
Migraine 1 5.00 Very Low Very Low Very Low
COX-2 inhibitor 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Albuminuria 27 99.04 Very High Very High Very High
Drug Induced Neurotoxicity 1 93.48 High High
Renal Disease 39 90.12 High High
Diabetes Mellitus 52 80.40 Quite High
Disease 30 76.96 Quite High
Body Weight 1 63.52 Quite High
Disorders Of Creatine Metabolism 1 59.48 Quite High
Death 6 54.08 Quite High
Ataxia 33 43.68 Quite Low
Proteinuria 3 35.88 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Curcumin-treated rats had improvement in a number of biochemical parameters including attenuation of renal mRNAs for fibronectin, eNOS, TGF-beta, heme oxygenase-1, and improvements in glomerular nitrotyrosine, 8-OHdG, transcription coactivator p300, and NF?
Transcription (transcription) of p300
1) Confidence 0.24 Published 2010 Journal BMC Complement Altern Med Section Body Doc Link PMC2999583 Disease Relevance 1.09 Pain Relevance 0
Interactions of ataxin-3 and other regulators of histone acetylation and transcription (p300, CREB-binding protein) have been detected (Li et al 2002).


Transcription (transcription) of p300
2) Confidence 0.10 Published 2005 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2413192 Disease Relevance 0.29 Pain Relevance 0

General Comments

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