INT235166

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Context Info
Confidence 0.02
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.28
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Hdac3, Atxn1) cytoplasm (Hdac3, Atxn1) nucleoplasm (Atxn1)
RNA binding (Atxn1) DNA binding (Hdac3)
Anatomy Link Frequency
thyroid 1
Hdac3 (Mus musculus)
Atxn1 (Mus musculus)
Pain Link Frequency Relevance Heat
Calcium channel 5 5.00 Very Low Very Low Very Low
Migraine 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Repression 1 95.36 Very High Very High Very High
Targeted Disruption 8 67.08 Quite High
Ataxia 33 58.28 Quite High
Disease 28 43.00 Quite Low
Spinocerebellar Ataxia Type 2 17 10.52 Low Low
Retina Disease 3 5.00 Very Low Very Low Very Low
Machado-joseph Disease 3 5.00 Very Low Very Low Very Low
Cerebellar Ataxia 3 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Ocular Toxicity (including Many Sub-types) 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Latest results demonstrate that ataxin-1 interacts with the transcriptional corepressor SMRT (silencing mediator of retinoid and thyroid hormone receptors) and with histone deacetylase 3.
histone deacetylase 3 Binding (interacts) of ataxin-1 in thyroid
1) Confidence 0.02 Published 2005 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2413192 Disease Relevance 0.28 Pain Relevance 0

General Comments

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