INT235182

Context Info Confidence 0.05 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0.08 Pain Relevance 0

cytosol (IRF6, VIM) cytoplasm (IRF6, VIM) plasma membrane (VIM) cytoskeleton (VIM) nucleus (IRF6) DNA binding (IRF6)

IRF6 (Homo sapiens) VIM (Homo sapiens)

Pain Link Frequency Relevance Heat cytokine 26 5.00 Inflammation 5 5.00 corticosteroid 2 5.00 Kinase C 1 5.00 cINOD 1 5.00 dexamethasone 1 5.00

Disease Link Frequency Relevance Heat Stress 1 82.68 Infection 12 5.00 INFLAMMATION 6 5.00 Apoptosis 3 5.00 Cancer 3 5.00 Communicable Diseases 1 5.00 Necrosis 1 5.00 Aging 1 5.00 Injury 1 5.00 Autoimmune Disease 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Our results suggested that vimentin was increased by LPS priming (spots O and S at 48–50 kDa on the gels), and that in the absence of LPS, vimentin was cleaved into smaller fragments (spot E at 24 kDa on the gels) (Table 1 and Additional File 5).

LPS Positive_regulation (increased) of vimentin

1) Confidence 0.05 Published 2008 Journal Proteome Sci Section Body Doc Link PMC2413206 Disease Relevance 0.08 Pain Relevance 0

General Comments

This test has worked.