INT235216

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.78
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 7
Total Number 7
Disease Relevance 4.30
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Cybb) mitochondrion (Cybb) oxidoreductase activity (Cybb)
Golgi apparatus (Cybb) endoplasmic reticulum (Cybb) plasma membrane (Cybb)
Anatomy Link Frequency
lumen 1
microglia 1
Cybb (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 53 89.92 High High
imagery 3 89.20 High High
Substantia nigra 41 79.68 Quite High
midbrain 3 62.00 Quite High
cINOD 1 50.88 Quite High
dopaminergic neurodegeneration 5 50.00 Quite Low
Inflammatory marker 3 50.00 Quite Low
addiction 5 30.92 Quite Low
cytokine 14 21.28 Low Low
Dopamine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Mycobacterial Infection 282 99.26 Very High Very High Very High
Ulcers 4 99.12 Very High Very High Very High
Diabetes Mellitus 71 98.36 Very High Very High Very High
Atherosclerosis 19 96.24 Very High Very High Very High
Apoptosis 265 95.92 Very High Very High Very High
Hypertrophy 1 95.48 Very High Very High Very High
Brain Injury 53 95.36 Very High Very High Very High
Calcification 93 94.48 High High
Pathologic Processes 1 90.88 High High
INFLAMMATION 59 89.92 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
From the results presented in Fig. 2 we suggested that gp91phox co-localized with classical activated microglia.
Localization (localized) of gp91phox in microglia
1) Confidence 0.78 Published 2010 Journal J Neuroinflammation Section Body Doc Link PMC2917406 Disease Relevance 0.16 Pain Relevance 0
All of the redox stations of the oxidase are located on gp91phox and, in the resting state, are not engaged in electron transport.
Localization (located) of gp91phox
2) Confidence 0.31 Published 2008 Journal J Neuroinflammation Section Body Doc Link PMC2413210 Disease Relevance 0.10 Pain Relevance 0.08
Furthermore, a common strategy used by several pathogenic bacteria, including M. tuberculosis, is the enzymatic detoxification of NOX2 generated superoxides via the secretion of enzymes such as superoxide dismutases and catalases[53].
Localization (secretion) of NOX2 associated with mycobacterial infection
3) Confidence 0.23 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2858756 Disease Relevance 0.65 Pain Relevance 0
A novel mechanism employed by Helicobacter pylori is to misdirect the assembly of functional NOX2 complex away from the membrane of phagosome to the plasma membrane, so that superoxides are being released into the extracellular space instead of the phagosomal lumen[6].
Localization (released) of NOX2 in lumen associated with ulcers
4) Confidence 0.19 Published 2010 Journal PLoS Pathogens Section Body Doc Link PMC2858756 Disease Relevance 0.72 Pain Relevance 0
B p50 and gp91PHOX staining, the slides were observed using a Nikon Eclipse E800 M fluorescent microscope.
Localization (staining) of gp91PHOX
5) Confidence 0.14 Published 2010 Journal Mol Neurodegener Section Body Doc Link PMC2975641 Disease Relevance 0 Pain Relevance 0.12
NADPH oxidase is composed of mainly four subunits, two of them are localized in the membrane (gp91phox and p22phox) and the others are in the cytosol (p47phox, p67phox) [29].
Localization (localized) of gp91phox
6) Confidence 0.12 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2954163 Disease Relevance 0.73 Pain Relevance 0.04
YKL-40 is a 40 kDa heparin- and chitin-binding glycoprotein which is secreted in vitro by a variety of cells.
Localization (secreted) of chitin-binding glycoprotein
7) Confidence 0.01 Published 2010 Journal Cardiovasc Diabetol Section Body Doc Link PMC3016330 Disease Relevance 1.94 Pain Relevance 0.07

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox